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Assistant Professor
UAMS College of Medicine
Pharmacology and Toxicology
UAMS, Little Rock
- Xiong Y, Chang Y, Hao J, Zhang C, Yang F, Wang Z, Liu Y, Wang X, Xu Q*, Mu S*. Eplerenone attenuates fibrosis in the contralateral kidney of UUO rats by preventing macrophage-to-myofibroblast transition. Frontiers Pharmacology. 2021 (in press)
- Garner B, Stolarz AJ, Stuckey D, Sarimollaoglu M, Liu Y, Palade P, Rusch NJ, Mu S. KATP Channel Openers Inhibit Lymphatic Contractions and Lymph Flow as a Possible Mechanism of Peripheral Edema. J Pharmacol Exp Ther. 376(1): 40-50, 2021. PubMed PMID: 33100270.
- Ding Z, Wang X, Liu S, Zhou S, Kore R, Mu S, Deng X, Fan Y, Mehta JL. NLRP3 inflammasome via IL-1β regulates PCSK9 secretion. 10(16): 7100-7110, 2020. PubMed PMID: 32641981.
- Dai L, Chen J, Lin Z, Wang Z, Mu S, Qin Z. Targeting Sphingosine Kinase by ABC294640 against Diffuse Intrinsic Pontine Glioma (DIPG). Journal of Cancer 11(16): 4683-4691, 2020. PubMed PMID: 32626514.
- Cozart MA, Phelan KD, Wu H, Mu S, Birnbaumer L, Rusch NJ, Zheng F. Vascular smooth muscle TRPC3 channels facilitate the inverse hemodynamic response during status epilepticus. Sci Rep. 10(1): 812, 2020. PubMed PMID: 31964991
- Liu S, Deng X, Zhang P, Wang X, Fan Y, Zhou S, Mu S, Mehta JL, Ding Z. Blood flow patterns regulate PCSK9 secretion via MyD88 mediated proinflammatory cytokines. Cardiovasc Res. 116(10): 1721-1732, 2020. PMID: 31593224
- Zheng F, Mu S, Rusch NJ. Leptin Activates Trpm7 Channels in the Carotid Body As a Mechanism of Obesity-Related Hypertension. Circ Res. 125(11): 1003-1005, 2019. PMID: 31697634
- Mu S, Fantegrossi W, Rusch N. Cocaine-Responsive miRNA and Blood Pressure Elevation. 71(4): 561-562; 2018. PMID: 29483229
- Sims CR, Singh SP, Mu S, Gokden N, Zakaria D, Nguyen TC and Mayeux PR. Rolipram Improves Outcome in a Rat Model of Infant Sepsis-Induced Cardiorenal Syndrome. Frontiers in Pharmacology. 8: 237; 2017. PubMed PMID: 28515693
- Liu Y, Rafferty TM, Rhee SW, Webber JS, Song L, Ko B, Hoover RS, He B, Mu S. CD8+ T cells stimulate Na-Cl co-transporter NCC in distal convoluted tubules leading to salt-sensitive hypertension. Nature Communications. 8: 14037; 2017. PubMed PMID: 28067240
- Hirohama D, Kawakami-Mori F, Ogura S, Mu S, Jimbo R, Uetake U, Yatomi Y, Nangaku M, Fujita T and Shimosawa T. Renal denervation improves cardiac diastolic dysfunction by restoring serca2a transcription in uninephrectomized rats. Journal of Hypertension (Los Angel). 5: 225 (1-5), 2016. PMC Journal
- Uetake Y, Ikeda H, Irie R, Tejima K, Matsui H, Ogura S, Wang H, Mu S, Hirohama D, Ando K, Sawamura T, Yatomi Y, Fujita T, Shimosawa T. High-salt in addition to high-fat diet may enhance inflammation and fibrosis in liver steatosis induced by oxidative stress and dyslipidemia in mice. Lipids in Health and Disease. 14: 6, 2015. PubMed PMID: 25888871
- Jimbo R, Kawakami-Mori F, Mu S, Hirohama D, Majtan B, Shimizu Y, Yatomi Y, Fukumoto S, Fujita T, Shimosawa T. Fibroblast growth factor 23 accelerates phosphate-induced vascular calcification in the absence of Klotho deficiency. Kidney International. 85(5): 1103-1111, 2014. PubMed PMID: 24088960
- Ogura S, Shimosawa T, Mu S, Sonobe T, Kawakami-Mori F, Wang H, Uetake Y, Yoshida K, Yatomi Y, Shirai M, Fujita T. Oxidative stress augments pulmonary hypertension in chronically hypoxic mice overexpressing the oxidized LDL receptor. American Journal of Physiology Heart and Circulatory Physiology. 305(2): H155-62, 2013. PubMed PMID: 23686713
- Shimosawa T, Mu S, Fujita T. High salt intake and Hypertension. Kagaku to Seibutsu. 50(4): 250-254, 2012. [Japanese] PMC Journal
- Shimosawa T, Mu S, Shibata S, Fujita T. The Kidney and hypertension: pathogenesis of salt-sensitive hypertension. Current Hypertension Reports. 14: 468-472, 2012. PubMed PMID: 22752520
- Mori-Kawakami F, Shimosawa T, Wang H, Ogura S, Mu S, Yatomi Y, Fujita T. NADPH oxidase-mediated Rac1 GTP activity is necessary for non-genomic actions of the mineralocorticoid receptor in the CA1 region of the rat hippocampus. Am J Physiol Endoc Metab. 302: E425-32, 2012. PubMed PMID: 22114025
- Shimosawa T, Matsui H, Jing L, Guangquin X, Qingyou X, Jing Q, Mori F, Jimbo R, Mu S, Anan S, Reheman L, Uetake U, Ogura S, Fujita T. Adrenomedullin and Oxidative Stress in Vascular Damage and Metabolic Disease. Current Hypertension Reviews. 7:251-256, 2011. PCM Journal
- Shibata S*, Mu S*, Kawarazaki H*, Muraoka K, Ishizawa K, Yoshida S, Kawarazaki W, Takeuchi M, Ayusawa N, Miyoshi J, Takai Y, Ishikawa A, Shimosawa T, Ando K, Nagase M, Fujita T (*equal contributors). Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptor-dependent pathway. Journal of Clinical Investigation. 121:3233-3243, 2011. PubMed PMID: 21765214
- Mu S, Shimosawa T, Ogura S, Wang H, Uetake Y, Kawakami-Mori F, Marumo T, Yatomi Y, Geller DS, Tanaka H, Fujita T. Epigenetic modulation of the renal β-adrenergic-WNK4 pathway in salt-sensitive hypertension. Nature Medicine. 17:573–580, 2011. PubMed PMID: 21499270
- Shimosawa T, Kaneko T, Uetake Y, Miyamoto Y, Matsui H, Wang H, Mu S, Saito R, Ogura S, Yatomi Y, Fujita T. Atherosclerosis and oxidative stress. Nihon Ronen Igakkai Zasshi. 45: 287-290, 2008. [Japanese] PubMed PMID: 18622111